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DNA2 inhibitor C5

CAS No. 35973-25-2

DNA2 inhibitor C5 ( —— )

Catalog No. M24317 CAS No. 35973-25-2

DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress and it also is a competitive and specific inhibitor of DNA2 nuclease activity (IC50: 20 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 69 In Stock
5MG 110 In Stock
10MG 178 In Stock
25MG 410 In Stock
50MG 605 In Stock
100MG 860 In Stock
500MG 1728 In Stock
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Biological Information

  • Product Name
    DNA2 inhibitor C5
  • Note
    Research use only, not for human use.
  • Brief Description
    DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress and it also is a competitive and specific inhibitor of DNA2 nuclease activity (IC50: 20 μM).
  • Description
    DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress and it also is a competitive and specific inhibitor of DNA2 nuclease activity (IC50: 20 μM). DNA2 inhibitor C5 inhibits nuclease, DNA dependent ATPase, helicase, and DNA binding activities of DNA2.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    DNA2 nuclease
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    35973-25-2
  • Formula Weight
    234.2
  • Molecular Formula
    C10H6N2O5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:31.25 mg/mL (133.45 mM; Need ultrasonic)
  • SMILES
    O=C(C1=C(O)C2=CC=CC([N+]([O-])=O)=C2N=C1)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Binghui Shen, et al. Dna2 inhibitors for cancer treatment. US20170226063A1.
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