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DNA2 inhibitor C5
CAS No. 35973-25-2
DNA2 inhibitor C5( —— )
Catalog No. M24317 CAS No. 35973-25-2
DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress and it also is a competitive and specific inhibitor of DNA2 nuclease activity (IC50: 20 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 69 | In Stock |
|
| 5MG | 110 | In Stock |
|
| 10MG | 178 | In Stock |
|
| 25MG | 410 | In Stock |
|
| 50MG | 605 | In Stock |
|
| 100MG | 860 | In Stock |
|
| 500MG | 1728 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameDNA2 inhibitor C5
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NoteResearch use only, not for human use.
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Brief DescriptionDNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress and it also is a competitive and specific inhibitor of DNA2 nuclease activity (IC50: 20 μM).
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DescriptionDNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress and it also is a competitive and specific inhibitor of DNA2 nuclease activity (IC50: 20 μM). DNA2 inhibitor C5 inhibits nuclease, DNA dependent ATPase, helicase, and DNA binding activities of DNA2.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorDNA2 nuclease
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Research Area——
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Indication——
Chemical Information
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CAS Number35973-25-2
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Formula Weight234.17
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Molecular FormulaC10H6N2O5
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Purity>98% (HPLC)
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SolubilityDMSO:31.25 mg/mL (133.45 mM; Need ultrasonic)
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SMILESO=C(C1=C(O)C2=CC=CC([N+]([O-])=O)=C2N=C1)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Binghui Shen, et al. Dna2 inhibitors for cancer treatment. US20170226063A1.
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